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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
32.42
Human Site:
Y93
Identified Species:
54.87
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
Y93
Q
R
D
P
N
N
P
Y
D
K
N
A
I
K
V
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
Y93
Q
R
D
P
N
N
P
Y
D
K
N
A
I
K
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
Y192
Q
R
E
P
N
N
P
Y
D
K
N
A
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
Y93
Q
R
E
P
N
N
P
Y
D
K
N
A
I
K
V
Rat
Rattus norvegicus
NP_001099948
974
110023
Y93
E
R
E
P
N
N
P
Y
D
K
N
A
I
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
T83
I
H
A
A
V
Q
M
T
T
E
Q
L
K
T
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
Y107
Q
R
E
P
N
N
Q
Y
D
R
N
A
V
K
I
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
Y87
V
R
E
P
H
N
P
Y
D
R
N
A
V
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
S125
E
Q
R
A
L
S
P
S
T
R
M
S
I
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
Y125
V
R
E
P
L
N
R
Y
D
K
N
A
V
K
V
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
E80
S
G
R
I
N
G
R
E
M
V
G
L
V
R
E
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
F140
V
E
S
P
Q
L
A
F
D
K
D
T
F
E
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
66.6
60
N.A.
13.3
N.A.
N.A.
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
93.3
86.6
N.A.
46.6
N.A.
N.A.
80
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
0
N.A.
N.A.
6.6
0
20
P-Site Similarity:
0
N.A.
N.A.
20
0
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
0
8
0
0
0
0
58
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
65
0
8
0
0
0
0
% D
% Glu:
15
8
43
0
0
0
0
8
0
8
0
0
0
8
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
8
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
0
0
43
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
50
0
0
8
50
0
% K
% Leu:
0
0
0
0
15
8
0
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
8
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
50
58
0
0
0
0
58
0
0
0
0
% N
% Pro:
0
0
0
65
0
0
50
0
0
0
0
0
0
0
0
% P
% Gln:
36
8
0
0
8
8
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
58
15
0
0
0
15
0
0
22
0
0
0
8
0
% R
% Ser:
8
0
8
0
0
8
0
8
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
15
0
0
8
0
15
0
% T
% Val:
22
0
0
0
8
0
0
0
0
8
0
0
29
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _